Prostaglandins and Therapeutic use of Prostaglandins

Prostaglandins

Actions of Prostaglandins Prostaglandins act by binding to different G-protein coupled receptors that in return activate or inhibit adenylyl cyclase or stimulate phospholipase C. That eventually results in an enhanced formation of diacylglycerol and inositol 1,4,5-trisphosphate. Prostaglandin F2α (PGF2α), the leukotrienes, and thromboxane A2 (TXA2) activate phosphatidylinositol metabolism to perform certain functions. Thus, activation of … Read more Prostaglandins and Therapeutic use of Prostaglandins