Biosynthesis of cholesterol and its regulation

Cholesterol levels in the body originate from its biosynthesis and diet. Most of the cholesterol used by active adults is produced in the liver, which produces ~70% of daily cholesterol demand (~1 gram). The other 30% originates from dietary absorption. Biosynthesis of cholesterol commonly happens in the endoplasmic reticulum of hepatic cells. It starts with … Read more Biosynthesis of cholesterol and its regulation

Having the symptoms doesn’t always confirm COVID-19

SARS-CoV-2 and COVID-19

The symptoms of the cold that we frequently have, the flu, and COVID-19 have got quite a number of overlaps. Therefore symptoms alone cannot confirm whether a person is having a novel coronavirus or nCoV infection. There has to be an array of symptoms that need to get weaved together to have a confirmed case … Read more Having the symptoms doesn’t always confirm COVID-19

Hypersensitivity Type I, Type II, Type III, Type IV

Hypersensitivity Type I, Type II, Type III, Type IV

Allergy is the response of the immune system to small or harmless substances like dust, pollens, smoke, etc. It’s in fact called hypersensitivity reactions. Hypersensitivity refers to undesirable reactions produced by the normal immune system. Type I ◦ Allergy (immediate) Type II ◦ cytotoxic, antibody-dependent Type III ◦ Immune complex diseases Type IV ◦ Delayed … Read more Hypersensitivity Type I, Type II, Type III, Type IV

Plasmodium and Malaria

Plasmodium and Malaria

The early history of Plasmodium and Malaria In the past time, it was believed that malaria spread by bad air hence the name means bad air. In 1880 Malaria parasites firstly discovered by a french doctor, Charles Laveran. In 1897 Ronald Ross worked on avian malarial parasites (P. praecox), Ronald Ross was awarded Noble prize … Read more Plasmodium and Malaria

Gluconeogenesis- De novo synthesis of Glucose

Gluconeogenesis- De novo synthesis of Glucose

Gluconeogenesis definition Gluconeogenesis is the synthesis of glucose from non-carbohydrate precursors. Gluconeogenesis is a universal pathway found in all animals, plants, fungi, and microorganisms. Site of gluconeogenesis In higher animals, gluconeogenesis occurs in the liver and to a lesser extent in the kidney cortex. Eventually, under normal circumstances, the liver is responsible for 85% to … Read more Gluconeogenesis- De novo synthesis of Glucose

Vectors- characteristics, classification, features, types

Vectors

Vectors are DNA molecules that are used as a vehicle to carry foreign DNA fragments into other cells where they can replicate and/or express. Among these most commonly used vector is a plasmid. Characteristics of vectors: Self replicating, multiple copies. Replication origin site. Cloning site. Selectable marker gene. Low molecular weight. Easily isolates and purifies. … Read more Vectors- characteristics, classification, features, types

Differences between Real-Time PCR and Rapid Diagnostic Test

Differences between Real-Time PCR and Rapid Diagnostic Test

Rapid Diagnostic Test vs Real-Time PCR (qPCR) There are several diagnostic tests that have been authorized for Emergency Use by the FDA for diagnosis of a wide range of infections. Notably, these diagnostic tests aim at identifying an infected individual from a non-infected person, using different working principles and duration for the tests vary. Diagnostic … Read more Differences between Real-Time PCR and Rapid Diagnostic Test

COVID-19 diagnosis: Abbott RealTime SARS-CoV-2 assay

Abbott RealTime SARS-CoV-2 assay

Medical Disclaimer: The information presented on the website is only for academic and study purposes and must not be used for the purpose of diagnosis. If you are not feeling well, please consult with your physician or doctor. Introduction We have so far discussed the most current diagnostic tests that have been authorized by the … Read more COVID-19 diagnosis: Abbott RealTime SARS-CoV-2 assay

COVID-19 IgG/IgM Rapid Test for antibodies detection

COVID-19 IgG-IgM Rapid Test for antibodies detection

Medical Disclaimer: The information presented on the website is only for academic and study purposes and must not be used for the purpose of diagnosis. If you are not feeling well, please consult with your physician or doctor. Introduction So far we have discussed three tests currently authorized by the Food and Drug Administration (FDA) … Read more COVID-19 IgG/IgM Rapid Test for antibodies detection

COVID-19 Diagnostic Test: Xpert Xpress SARS-CoV-2

Medical Disclaimer: The information presented on the website is only for academic and study purposes and must not be used for the purpose of diagnosis. If you are not feeling well, please consult with your physician or doctor. Introduction COVID-19 disease caught the world unaware, unprepared for a pandemic as bad at what we have … Read more COVID-19 Diagnostic Test: Xpert Xpress SARS-CoV-2