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Bioinformatics

Bioinformatics is an emerging field of science that deals with the application of computers to the collection, organization, analysis, manipulation, presentation, and sharing of biological data.

  • Bioinformatics is an interdisciplinary field directly involving molecular biology, genetics, computer science, mathematics, and statistics.
  • The central component of bioinformatics is the study of the best ways to design and operate biologic databases.
  • As a large amount of nucleotide and protein sequence data are obtained via various research techniques, along with other types of information stored in primary and secondary biological databases, scientists started to use computers to obtain and analyze biological data in their daily research with bioinformatics tools.
  • To help the biologists access the databases effectively and use the analysis tools efficiently, bioinformatics has eventually become a vital part of biological education.
  • Bioinformatics is an evolving discipline, and complex software programs are now being used for retrieving, sorting out, analyzing, predicting, and storing DNA and protein sequence data.
  • One of the fundamental activities in bioinformatics is the sequence analysis of DNA and proteins using various programs and databases available on the world wide web.
  • Large commercial enterprises such as pharmaceutical companies employ bioinformaticians to perform and maintain the large scale and complex bioinformatics needs of these industries.
  • Apart from the analysis of genome sequence data, bioinformatics is now being used for a vast array of other vital tasks, including analysis of gene variation and expression, analysis, and prediction of gene and protein structure and function.
  • Besides, bioinformatics has found its importance in tasks like prediction and detection of gene regulation networks and presentation and analysis of molecular pathways in order to understand gene-disease interactions.
  • Bioinformatics even has clinical applications as the whole genome sequencing of an organism allows for the production of a complete list of human gene products that may provide new drugs and gene therapy for single-gene diseases may become routine.
  • Bioinformatics can be used for different other fields of the biology of different groups of living beings.

In Silico Drug Design- Definition, Methods, Types, Uses

May 27, 2023 by Sanju Tamang
In Silico Drug Design

Drug design and development is a complex and costly process that involves identifying and developing new chemical compounds that can be used as drugs to treat diseases. Traditional drug design … Read more

Homology Modeling- Definition, Steps, Diagram, Uses

May 21, 2023 by Sanju Tamang
Homology Modeling

Protein structure prediction is an important aspect of computational biology that aims to determine the three-dimensional (3D) structure of a protein. Homology modeling is one of the computational methods of … Read more

Nucleotide Databases- Definition, Types, Examples, Uses

April 29, 2023 by Sanju Tamang
Nucleotide Databases

Biological databases store and organize biological data for easy retrieval of information. These centralized resources contain DNA and protein sequences and their associated information.  Nucleotide databases are a type of … Read more

Protein Databases- Definition, Types, Examples, Uses

April 29, 2023 by Sanju Tamang
Protein Databases

Protein databases are a type of biological database that are collections of information about proteins. The information contained in protein databases includes the amino acid sequence, the domain structure, the … Read more

Secondary Databases- Definition, Types, Examples, Uses

April 28, 2023 by Sanju Tamang
Secondary Databases

Biological databases store and organize biological data for easy retrieval of information. These centralized resources contain DNA and protein sequences, and their associated information.  Primary databases store and make raw … Read more

Primary Databases- Definition, Types, Examples, Uses

April 22, 2023 by Sanju Tamang
Primary Databases

Modern genomic research generates vast amounts of raw sequence data, which has created the need for biological databases to store and organize this enormous data. Biological databases are collections of … Read more

Phylogenetic Tree- Definition, Types, Steps, Methods, Uses

April 11, 2023 by Sanju Tamang
Phylogenetic Tree Parts

A phylogenetic tree (evolutionary tree) is the graphical representation of the evolutionary history of biological sequences and allows us to visualize the evolutionary relationships between them. Evolution explains the diversity … Read more

Python and R Programming Language in Bioinformatics

April 4, 2023 by Sanju Tamang
Python and R Programming Language in Bioinformatics

Bioinformatics is a rapidly growing field that integrates biological science and computer science for the development and application of computational tools in order to analyze and interpret biological data. Programming … Read more

Bioinformatics Databases, Software, and Tools with Uses

March 26, 2023 by Sanju Tamang
Bioinformatics Databases, Software, and Tools

The increase in the amount of biological data created a need for developing computational tools for managing and analyzing the data, which led to the creation of a new field … Read more

Sequence Alignment- Definition, Types, Methods, Uses

March 17, 2023 by Sanju Tamang
Global and Local Alignment

Sequence comparison is a crucial aspect of bioinformatics analysis that involves comparing newly determined biological sequences with previously known sequences stored in databases.  Sequence alignment is considered the most essential … Read more

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